Quitting smoking with a vaccine is closer

Quitting smoking is one of the most difficult decisions that can be made in life.

The nicotine it is an enormously addictive substance and binds it to those who consume it so strongly that leaving it can lead to suffering depression and other associated disorders.

So scientists have spent years looking for a way to do the process. easier those who want to look after their health, but their will does not allow it. Fortunately, the moment could be closer, thanks to the vaccine created by a group of researchers from the Scripps Research Institute, in California.

Why do we become addicted to tobacco?

As with other addictions, the fault lies with the brain reward systems,which are the ones that mediate the sensation of satisfaction that our brain generates when it comes into contact with the substance that causes addiction, in this case, the nicotine.

Therefore, the best way to prevent addiction from occurring is by making sure that this substance never reaches the brain.

How does the vaccine to quit smoking work?

The objective of this vaccine is to generate antibodies capable of fight nicotine and destroy it before it activates the reward systems.

A few years ago a couple of similar vaccines, but their results were not promising, since it only worked in 30% of the cases. This occurred due to the existence of two types of nicotine, which can be dextrgira or levgira, depending on whether the molecule is turned right or left, respectively.

The vaccines existing up to now, worked against both types of nicotine; but generally, cigarettes from habitual consumption they only contain the levgira, so you get a shot a lot more efficient focusing all attention on it. In fact, according to the results published in Journal of Medicinal Chemistry last year a 60% mice would be protected from addiction.

Also, this year those same scientists have added a new improvement to the vaccine, altering the molecules that signal the immune system to attack nicotine. In this way, basically, they have achievedtrain the body to powerfully destroy the source of addiction.

The results are very promising, although two very important experiments are still missing. First, they must test the vaccine on ratsThey are better models than mice to understand the behavior that will have in humans. Second, you also need to check the results at different doses to know which is the most suitable.

If all this works correctly, perhaps in a short time we could have access to this vaccine, which will make smoking stop being pleasant. Can you imagine how the cases of lung cancer will decrease from that moment?